Research at CEITEC MU
Research at CEITEC Masaryk University focuses at Life Sciences primarily on Life Sciences.
You can find more about research at CEITEC HERE.
Structural biology programme harbours research groups that study the intricate and exquisite choreography of life at cellular, molecular and atomic levels. We visualize structural details ranging from cells, their compartments, down to individual proteins, nucleic acids, and their complexes. Through the integration of structural and computational data we reveal the atomic details of the mechanisms by which healthy cells function and diseases progress. This basic understanding helps to develop novel therapeutic strategies to meet the challenges of an ageing society, public health and global pandemics.
Genomics and Proteomics of Plant Systems
The research area is focused on understanding the evolutionary-based strategies of plants. The knowledge acquired by –omic approaches, combined with our research experience in the areas of developmental and stress biology of plants, is subsequently used to develop new agricultural, biotechnology and biomedical applications in collaboration with potential users and top research workplaces in the field.
The main goal is to gain better understanding of basic molecular mechanisms in many diseases, especially cancer. Researchers of the programme focus on various types of leukemias and several solid tumours, they investigate immune cell microenvironment, transcription regulation, B and T cell receptor repertoires, and the effect of RNA modifications on innate immunity. For various malignancies, much effort has also been made to identify diagnostic and prognostic markers (miRNA profiling, lincRNA, mutations in TP53 and other cancer-related genes) and introduce them in clinical practise.
Brain and Mind Research
Aims to develop a unique workplace in the European context reaching from basic to transitional research of central nervous system; from animal studies to clinical, social and behavioural research of healthy and diseased brain, in particular dementia, epilepsy, movement disorders, schizofrenia, depression pain…. are studied with a core facility enabling most advanced structural, functional and metabolic brain mapping.
Advanced Nano and Microtechnologies
The research is focused on the area of nanotechnologies covering materials and structures to be exploited in nanoelectronic and nanophotonic applications. The research involves the preparation, characterization and analysis of the properties of nanostructures enabling active application of principles, which determine unique and specific properties of nanostructures.